Ezequiel Barco and Miguel Borja scored either side of halftime as leaders River Plate secured their ninth straight victory in Argentina's Primera Division with a 2-0 defeat of Independiente.
Barco gave the hosts the lead in the 17th minute when he fired a long-range effort into the top-right corner, reports Xinhua.
Independiente were reduced to 10 men after Damian Perez was shown a second yellow card for a bad foul on Nacho Fernandez.
Colombian striker Borja doubled the advantage with a low strike 10 minutes from time.
The result leaves River Plate with 33 points from 13 matches, six points ahead of second-placed San Lorenzo. Independiente are 26th, 23 points off the pace.
Earlier, Jorge Figal scored in the 100th minute to earn Boca Juniors a 2-2 draw at Rosario Central.
Lautaro Giaccone put Rosario Central ahead with a 25th-minute strike before Martin Payero equalized just after the hour.
Teenage striker Alejo Veliz restored the hosts' lead shortly afterwards, but Figal netted in the last minute as Boca avoided a fourth consecutive defeat.
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The result leaves Rosario Central fourth in the 28-team standings with 23 points, eight points ahead of 17th-placed Boca.