For the visitors, Bangladesh pace sensation Mustafizur Rahman, who joined the squad on Tuesday was drafted into the playing XI replacing Moises Henriques, who is unwell. Tamil Nadu's Vijay Shankar was the other change for SRH in place of Bipul Sharma.
Mumbai Indians, on the other hand, decided to go with an unchanged side after Sunday's thrilling win against Kolkata Knight Riders (KKR).
Sunrisers Hyderabad: David Warner (Captain), Shikhar Dhawan, Yuvraj Singh, Deepak Hooda, Vijay Shankar, Naman Ojha (WK), Ben Cutting, Bhuvneshwar Kumar, Rashid Khan, Ashish Nehra, Mustafizur Rahman.
Mumbai Indians: Rohit Sharma (Captain), Parthiv Patel (WK), Jos Buttler, Nitish Rana, Krunal Pandya, Kieron Pollard, Hardik Pandya, Harbhajan Singh, Lasith Malinga, Mitchell McClenaghan, Jasprit Bumrah.